ProSkin anti-age day cream

1. Probiotic lysates Bifidobacterium and Lactococcus effectively stimulate the skin’s immune system as well as the process of regeneration of the damaged skin area, resulting in the preservation of skin homeostasis.⁶
2. Bifidobacterium supplies skin cells with various nutrients (e.g. proteins) and other ingredients needed to produce new molecules and energy. They stimulate the natural desquamation of the skin and participate in the removal and reuse of cellular waste in the processes of detoxification of the surface layer of the skin. They are also responsible for creating a protective layer on the surface of the skin that can significantly reduce the level of harmful effects of UV radiation on the skin.⁶
3. Lactococcus activates the natural defence mechanism of the skin and participates in the activation of various enzymes on the surface of the skin which makes it firmer, more compact, more elastic and more resistant to external influences.⁶
4. Hyaluronic acid-treated skin, after 2, 4 and 8 weeks of topical application, is significantly more hydrated than untreated. Measurement of skin roughness showed a significantly finer skin structure after two weeks of topical application of hyaluronic acid creams, lotions and serums. In addition, the elasticity of the treated compared to untreated skin was measured and a significant improvement was shown after two weeks of application, and this trend continued throughout the study.⁴
5. Vitamin F is enriched with linoleic and α-linoleic fatty acids and participates as a support in the renewal of the surface layer of the skin, helping urea to maintain optimal levels of moisture, elasticity and maintaining the balance of fatty acids in the skin.²
6. Linoleic acid, thanks to its anti-inflammatory effect, significantly contributes to the reduction of symptoms such as redness of the skin in dermatitis and contributes to skin hydration (a study conducted on 20 patients with atopic dermatitis with an average age of 16.75 years over 4 weeks).⁵
7. Topical application of retinol (vitamin A) has a positive effect on reducing small wrinkles associated with aging. Significant induction of glycosaminoglycans, which retain large amounts of water, and increased collagen production are most likely responsible for wrinkle removal. With greater synthesis of the skin matrix, older skin treated with retinol is more likely to better tolerate skin injuries and the appearance of the skin will be improved.³
8. Shea butter deeply nourishes and regenerates the skin, thanks to its exceptional absorption properties it is quickly absorbed into the skin and enables and supports the penetration of other ingredients of urea, probiotics, borage oil and vitamin F into the deeper layers of the skin.¹

Literatura:

¹Andersson, A., Alanderi, J. (2015) Shea butter extract for bioactive skin care. AAK, Sweden./ ²Chiba, T., Nakahara, T., Kohda, F., Ichiki, T., Manabe, M., Furue, M. (2019) Measurement of trihydroxy-linoleic acids in stratum corneum by tape-stripping: Possible biomarker of barrier function in atopic dermatitis. PLoS ONE. 14(1). /³Kafi, R., Kwak, H. S. R., Schumacher, W. E., Cho, S., Hanft, V. N., Hamilton, T. A., Kang, S. (2007). Improvement of Naturally Aged Skin With Vitamin A (Retinol). Archives of Dermatology, 143(5)/ ⁴Manjula Jegasothy, S., Zabolotniaia, V., Bielfeldt, S. (2014) Efficacy of a New Topical Nano-hyaluronic Acid in Humans. J. Clin. Aesthet. Dermatol. 7(3): 27–29./ ⁵Nasrollahi, S. A., Ayatollahi, A., Yazdanparast, T., Samadi, A., Hosseini, H., Shamsipour, M., Akhlagi, A. A., Yadangi, S., Abels, C., Firooz, A. (2018) Comparison of linoleic acid-containing water-in-oil emulsion with urea-containing water-in-oil emulsion in the treatment of atopic dermatitis: a randomized clinical trial. Clin. Cosmet. Investig. Dermatol. 11:2128./ ⁶Richter, K. (2016) Effects of probiotics on skin health and their functions. Investig.Dermatol. 10:13-25.